Pass Box – Laminar Flow Systems

Laminar flow systems, both vertical and horizontal, provide active protection against particulate and microbiological contamination during transfer and storage phases in the pharmaceutical industry, between different cleanroom classes.

Their operation is based on a continuous flow of sterile filtered air that passes through the work area in a parallel manner, ensuring compliance with ISO 5 conditions, according to the ISO EN 14644-1 standard. This process guarantees a sterile and controlled environment during operations.

Pass Box

Custom-designed Pass-Box modules by COMECER, based on dimensional requirements, create an intermediate space between two processing classes, allowing for the decontamination or sterilization of materials to be transferred to the higher class. They can be made as small cabins or floor-level cabins to introduce trolleys loaded for sterilization. A continuous airflow and pressure differential keep the environment safe. Controlled fans ensure the necessary air exchanges, preventing contamination. The laminar flow is filtered through HEPA H14, with efficiency control and air conditioning via HVAC. Pneumatic doors are equipped with airtight seals, and sanitization occurs through the ultrafine atomization of biocides (hydrogen peroxide or peracetic acid), with materials compatible with the disinfectants used.

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